Cell Adhesion Molecule-1

A cell adhesion molecule that contains extracellular immunoglobulin V and C2 domains. It mediates homophilic and heterophilic cell-cell adhesion independently of calcium, and acts as a tumor suppressor in NON-SMALL-CELL LUNG CANCER (NSCLC) cells. Its interaction with NATURAL KILLER CELLS is important for their cytotoxicity and its expression by MAST CELLS plays a role in their interaction with neurons; it may also function in synapse assembly, nerve growth and differentiation.

Also Known As:

CADM1 Protein; IGSF4 Protein; TSLC1 Protein; Tumor Suppressor in Lung Cancer 1 Protein; Adhesion Molecule-1, Cell; Cell Adhesion Molecule 1; Molecule-1, Cell Adhesion

Carbohydrates: 22516
- Glycoconjugates: 1370
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Cell Adhesion Molecule-1: 430
Amino Acids, Peptides, and Proteins: 1
- Proteins: 496323
  - Glycoproteins: 25180
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Cell Adhesion Molecule-1: 430
  - Membrane Proteins: 10262
    - Membrane Glycoproteins: 2277
      - Cell Adhesion Molecules: 4912
        Cell Adhesion Molecule-1: 430
Biological Factors: 2560
- Antigens: 145631
  - Surface Antigens: 5857
    - Cell Adhesion Molecules: 4912
      - Cell Adhesion Molecule-1: 430

Kevin Pavlick Selected Research

Kevin Pavlick Research Topics

Disease

Drug/Important Bio-Agent (IBA)